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The Week鈥檚 10 Biggest Funding Rounds: Anthropic Rules With $500M Round; Aiolos Bio Nabs Large Raise

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Want to keep track of the largest startup funding deals in 2023 with our curated list of $100 million-plus venture deals to U.S.-based companies? Check out The 附近上门 Megadeals Tracker.

This is a weekly feature that runs down the week鈥檚 top 10 announced funding rounds in the U.S. Check out last week鈥檚 biggest funding rounds here.

After a slow week last week 鈥 where the top raise was only $57 million 鈥 this week saw a nice pickup thanks again to AI. Four companies raised nine-figure rounds and there were several other big rounds just under that. Of course, 鈥檚 round late in the week was the top raise, but biotech took three of the top five spots.

1. , $500M, artificial intelligence: Just last month, San Francisco-based company Anthropic 鈥 a rival with its AI assistant Claude 鈥 inked a deal with for the e-commerce and cloud titan to invest up to $4 billion in the AI startup. But why stop there when there are more billions of dollars to be had? The late Friday that previous investor agreed to invest up to $2 billion in the competitor. The deal includes $500 million upfront and an additional $1.5 billion more over time, per the report. The new investment is just the latest in what has become a fundraising spree for Anthropic this year. In February, it was reported that Google had invested between $300 million and $400 million in the startup. In May, the company raised a $450 million Series C led by . In August, Anthropic raised a $100 million round from . The Amazon deal followed late last month.

2. , $245M, biotech: Investors have always backed startups looking to take on asthma and other respiratory ailments. That continues with this week鈥檚 $245 million Series A for San Francisco- and London-based Aiolos Bio. , , and led the massive round. The newly launched company plans to use the fresh cash for phase 2 clinical trials of its lead drug candidate, AIO-001, designed for patients with moderate to severe asthma. More than 20 startups have been funded in the past several quarters and have raised close to $1.8 billion total, per 附近上门 . The company that has received the most funding on the list is Waltham, Massachusetts-based , which has raised more than $400 million to date.聽

3. (tied) , $100M, cybersecurity: Venture funding to cybersecurity startups is down 30% year to year, but this week saw a handful of good-sized rounds going to U.S.-based security firms. None were bigger than Dallas, Texas-based cybersecurity startup Island鈥檚 $100 million Series C led by and valuing it at $1.5 billion. Island offers an enterprise browser that the company says enhances both security and productivity of workers, giving security teams control of what is often referred to as the 鈥渓ast mile鈥 鈥 how end-users interact with work and web applications. The enterprise browser developer raised a $115 million Series B at a $1.3 billion valuation last year led by . Founded in 2020, the company has now raised $385 million, .

3. (tied) , $100M, autonomous vehicles: It may not have been a great week for the autonomous driving sector in general, as 鈥檚 driverless taxi service in San Francisco . However, it was a good week for Fremont, California-based Pony.ai, which announced a $100 million investment from the . The new deal is a joint venture to develop and deploy autonomous vehicles in Neom and other parts of the Middle East/North Africa region. Founded in 2016, the company has raised $1.3 billion, .

5. , $92M, biotech: Yet another biotech makes it high on the list. Waltham, Massachusetts-based Triveni Bio closed a $92 million series A financing co-led by and . The startup is developing treatments for atopic dermatitis, asthma and other inflammation and immunology disorders. This is the company鈥檚 first outside raise, .

6. , $85M, biotech: Next-generation biologics developer Rampart Biosciences locked up an $85 million Series A led by . The company has developed a proprietary DNA-based medicines platform 鈥 called HALO 鈥 which is designed to produce highly potent and redosable therapies. The company鈥檚 current lead program is for the treatment of hypophosphatasia, an often fatal genetic disease that prevents bone mineralization. Founded in 2019, the company has raised $125 million, .

7. , $70M, cybersecurity: Washington, D.C.-based Adlumin, a managed detection and response startup, raised a $70 million Series B led by . Founded in 2016, the company has raised nearly $129 million, .

8. , $55M, IT infrastructure: Seattle-based data processing unit developer MangoBoost has raised a $55 million Series A co-led by and . It was the new round gave the startup around a $300 million valuation. Founded in 2022, the company has raised nearly $66 million, .

8. (tied) , $50M, insurance: Denver-based insurance infrastructure startup AgentSync raised an additional $50 million co-led by existing investors and . Founded in 2018, AgentSync has raised $161 million, per the company.

8. (tied) , $50M, cybersecurity: Ann Arbor, Michigan-based threat hunting and exposure management startup Censys raised $75 million in a mix of equity and debt. The $50 million equity portion of the round was led by , , and . The $25 million in debt funding was led by . Founded in 2017, the company has raised $128 million, .

Big global deals

No round was bigger than Anthropic鈥檚 raise, but another across the pond was close.

  • London-based property and real estate firm locked up a venture round worth approximately $486 million.

Methodology

We tracked the largest announced rounds in the 附近上门 database that were raised by U.S.-based companies for the seven-day period of Oct. 21 to Oct. 27. Although most announced rounds are represented in the database, there could be a small time lag as some rounds are reported late in the week.

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