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This is a weekly feature that runs down the week鈥檚 top 10 announced funding rounds in the U.S. Check out last week鈥檚 biggest funding deal roundup here.
With the winter holiday season nearly upon us, this was likely the last busy week of 2025 for big funding announcements. And as weeks go, it was certainly an active one.
Perennial megaround raiser was the top funding recipient by far, securing a fresh $4 billion in Series L funding (yes, that is a thing) at a $134 billion valuation. Next on the list were data security platform and nuclear microreactor company , followed by startups in healthcare, biotech, fintech and AI.
1. , $4B, data and AI: Databricks that it is raising over $4 billion in a Series L financing at a $134 billion valuation, led by , and . The 12-year-old, San Francisco-headquartered company also said it crossed the $4.8 billion revenue run-rate in its third quarter,聽 growing聽 over 55% year over year.
2. , $400M, cybersecurity: New York-based Cyera, provider of an AI-enabled data security platform, reportedly $400 million in a funding round led by at a $9 billion valuation. The financing brings total funding to date for the 4-year-old company to $1.7 billion.
3. , $300M, nuclear power: Radiant, a maker of portable nuclear microreactors, it closed on over $300 million in Series D funding led by and . The El Segundo, California-based company said it plans to break ground early next year on a factory in Oak Ridge, Tennessee.
4. , $250M, healthcare software: Tebra, a provider of patient record software for healthcare private practices, says it raised $250 million in equity and debt financing to invest in AI and automation. led the equity financing, which constituted most of the round, while provided the debt funding for the Corona del Mar, California-based company.
5. (tied) , $150M, fintech: New York-based Imprint, a provider of credit cards affiliated with consumer brands, raised $150 million in Series D funding at a $1.2 billion valuation. led the round, with participation from , , , and .
5. (tied) , $150M, satellite intelligence: HawkEye 360, a provider of technology to detect, geolocate and characterize radio-frequency emissions, says it landed $150 million in Series E equity and debt financing. and co-led the equity funding, while provided the debt. The Herndon, Virginia company says it also completed its acquisition of .
7. , $130M, biotech and AI: Chai Discovery, a startup that uses AI to predict and reprogram interactions between biochemical molecules, landed $130 million in a Series B round. and led the financing, which set a $1.3 billion valuation for the San Francisco-based company.
8. (tied) , $125M, biotech: Irvine, California-based Ambros Therapeutics launched publicly with a $125 million Series A financing co-led by and ‘s strategic health care investment arm . The company licensed the rights to neridronate, which is used to treat Complex Regional Pain Syndrome.
8. (tied) , $125M, microprocessors: Mythic, an Austin-based startup developing semiconductor architecture to make AI computing more energy efficient, raised $125 million in a funding round led by and joined by a long list of venture investors.
10. , $120M, biotech: Cambridge, Massachusetts-based Atavistik Bio, a developer of聽 allosteric small molecule therapeutics, raised $120 million in Series B funding led by and . Founded in 2021, Atavistik has raised $220 million in known funding to date, per .
Methodology
We tracked the largest announced rounds in the 附近上门 database that were raised by U.S.-based companies for the period of Dec. 13-19. Although most announced rounds are represented in the database, there could be a small time lag as some rounds are reported late in the week.
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