Want to keep track of the largest startup funding deals in 2025 with our curated list of $100 million-plus venture deals to U.S.-based companies? Check out The 附近上门 Megadeals Board.
This is a weekly feature that runs down the week鈥檚 top 10 announced funding rounds in the U.S. Check out last week鈥檚 biggest funding deal roundup here.
The first week of March was a relatively brisk period for large startup funding rounds, led by three deals of $500 million or more in the space tech and AI infrastructure sectors. In addition, we saw some good-sized deals around healthcare, neuroscience and enterprise software.
1. , $550M, space tech: Sierra Space, a space and defense tech company that designs and manufactures satellites, spacecraft and space subsystems, secured $550 million in equity funding led by . The financing sets an $8 billion valuation for the 5-year-old, Louisville, Colorado-based company.
2. (tied) , $500M, AI infrastructure: Ayar Labs, a producer of co-packaged optics for use in AI infrastructure, landed $500 million in Series E funding led by . The financing sets a $3.75 billion valuation for the 11-year-old, San Jose, California-based company.
2. (tied) , $500M, space tech: Long Beach, California-based Vast, a startup developing next-generation space stations, announced it has raised $500 million in fresh funding. The financing includes $300 million in Series A equity and $200 million in debt, with as lead investor.
4. , $250M, care platform: Findhelp, developer of a platform to coordinate care across health systems, governments, benefits providers and other entities, secured $250 million in investment from 鈥檚 . Founded in 2010, Austin-based Findhelp describes its mission as connecting people to help and support systems.
5. , $230M, neurotech: Alameda, California-based Science Corp., a biotech startup focused on brain-computer interface technologies, announced it has closed on a $230 million Series C fundraise. , , , and were among the investors participating in the syndicated round.
6. , $180M, e-commerce: Cart.com, provider of an e-commerce platform and logistics services for brands to sell across digital channels, picked up $180 million in growth equity investment. led the financing for the Houston-based company.
7. , $150M, mental health care: Grow Therapy, a New York-based platform for providing mental health care, raised $150 million in Series D funding led by and .
8. , $105M, neuroscience: Cambridge, Massachusetts-based Cognito Therapeutics, a developer of therapies for neurodegenerative diseases, secured $105 million in Series C funding. , and led the financing.
9. , $80M, engineering software: Nominal, a self-described provider of tools for engineers to test and operate critical technology, picked up $80 million in new funding. led the financing, which set a $1 billion valuation for the Austin-based company.
10. , $65M, health software: New York-based Sage, provider of a software platform for senior living and skilled nursing, raised $65 million in Series C funding led by .
Methodology
We tracked the largest announced rounds in the 附近上门 database that were raised by U.S.-based companies for the period of Feb. 28-March 6. Although most announced rounds are represented in the database, there could be a small time lag as some rounds are reported late in the week.
Illustration:
Stay up to date with recent funding rounds, acquisitions, and more with the 附近上门 Daily.


67.1K Followers